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Posteroventral Medial Pallidotomy in Levodopa-Unresponsive Parkinsonism Arch Neurol 54:1026-1029, Krauss,J.K.,et al, 1997 See this aricle in Pubmed Article Abstract We treated the patient with microelectrode-guided unilateral posteroventral medial pallidotomy and followed up with magnetic resonance imaging and prospective clinical evaluation.Pallidotomy resulted in marked improvement of right-sided parkinsonian symptoms and functional disability at 4.5 months after surgery.Microelectrode recording during pallidotomy revealed discharge patterns that were similar to those seen in patients with Parkinson disease.Post-operative magnetic resonance imaging confirmed the location of the lesion in the posteroventral medial pallidum. Posteroventral pallidotomy usually has limited benefit in patients with degenerative atypical parkinsonism who do not respond to levodopa therapy. Nevertheless,pallidotomy can be an effective treatment for other levodopa- unresponsive parkinsonian disorders.

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(click to filter results - removes previous filter) head injury pallidotomy Parkinson disease Parkinson disease,L-dopa nonresponsive Parkinson disease,surgical treatment of Parkinson disease,treatment of stereotaxic surgery treatment of neurologic disorder

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